Fármaco antiviral. Análogo nucleósido de la guanina, activo frente al virus herpes humano. Inhibe la replicación de ADN viral interfiriendo con la ADN polimerasa viral. Muy activo frente al virus herpes simple y virus varicela zóster. Menos activo frente al virus de Epstein-Barr, y aún menos frente a citomegalovirus y otros virus herpes. <(F.): Aciclovir: analogue de la guanosine à propriété antimétabolite. Antiviral efficace, il est utilisé contre l'herpès.
<(In.): Aciclovir, acyclovir: chemical name acycloguanosine, is a guanine analogue antiviral drug, marketed under trade names such as Zovirax and Zovir. One of the most commonly-used antiviral drugs, it is primarily used for the treatment of herpes simplex virus infections, as well as in the treatment of herpes zoster. Acyclovir was seen as the start of a new era in antiviral therapy, as it is extremely selective and low in cytotoxicity. Pharmacologist Gertrude B. Elion was awarded the 1988 Nobel Prize in Medicine, partly for the development of acyclovir.
BANCOS DE DATOS DE MEDICAMENTOS:
- AGENCIA ESPAÑOLA DE MEDICAMENTOS: información online. <E)
- ELECTRONIC MEDICINES COMPENDIUM. (Ing)
- EUROPEAN MEDICINES AGENCY. <(Ing)
- INTERNET DRUG LIST. <(Ing)
- PR VDEMECUM LARINOAMERICA. <(E) - <(P)
- VADEMECUM INTERNACIONAL. <(E)
- VIDAL. <(F)
FUENTES DE INFORMACIÓN BIOMÉDICA:
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CISMeF. <(F)
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GOOGLE ACADEMICO. <(E)
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GOOGLE SCHOLAR. <(Ing)
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NCBI: Entrez. <(Ing)
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PubMed. <(Ing)
INFORMACIÓN PACIENTES:
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DOCTISSIMO. <(F)
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DRUGS. <(Ing)
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MedlinePlus. <(E)
- WIKIPEDIA. <(E)
TEXTOS:
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MEDIFAN. <(E)
TÉRMINOS RELACIONADOS.